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Sex and the Adult Female With Cancer

Sex hormones have been implicated in neurite outgrowth, synaptogenesis, dendritic branching, myelination and other important mechanisms of neural plasticity. Here we review the evidence from animal experiments and human studies reporting interactions between sex hormones and the dominant neurotransmitters, such as serotonin, dopamine, GABA and glutamate. We provide an overview of accumulating data during physiological and pathological conditions and discuss currently conceptualized theories on how sex hormones potentially trigger neuroplasticity changes through these four neurochemical systems. Many brain regions have been demonstrated to express high densities for estrogen- and progesterone receptors, such as the amygdala, the hypothalamus, and the hippocampus. As the hippocampus is of particular relevance in the context of mediating structural plasticity in the adult brain, we put particular emphasis on what evidence could be gathered thus far that links differences in behavior, neurochemical patterns and hippocampal structure to a changing hormonal environment.
Attention deficit hyperactivity disorder ADHD is a condition that causes a person to have a variety of symptoms which may include impulsive behavior, hyperactivity, and difficulty paying attention. This disorder can have significant effects on adult life. For example, a person with ADHD may have a poor self-image and difficulty maintaining a stable relationship or job. The effects on sexuality by ADHD can be hard to measure. This is because sexual symptoms may be different in each person.